Dr. Ashok Behera : Web-Literature
Dr. Ashok Behera is a highly accomplished researcher with a strong background in the field of pharmacy and medicinal chemistry. He earned his Ph.D. from Jadavpur University in Kolkata, West Bengal, India, where he worked at CSIR-IICB from June 13, 2011, to June 27, 2014, in the Pharmacy Department. Prior to his doctoral studies, he completed an MS Pharm in Medicinal Chemistry at the National Institute of Pharmaceutical Education and Research, Kolkata, from November 10, 2007, to June 30, 2009.
Dr. Behera has made significant contributions to the field, particularly in areas such as peptidomimetics, receptor-specific targeted drug delivery, computer-aided drug design, and analytical method development. His expertise also extends to organic synthesis and purification, analytical techniques, structure elucidation, and biological studies related to anticancer drug discovery. He has a comprehensive skill set that includes proficiency in various software applications relevant to research.
In terms of research grants and funding, Dr. Behera has been the Principal Investigator for projects such as “Synthesis, characterization and biological evaluation of smart novel nanotheranostic for cancer,” funded by DST-SERB-TARE, and “Synthesis, characterization and in-vitro evaluation of new 5FU-Octreotide conjugates for targeted chemotherapy,” under Project no. DITU/R&D/2021/2/ Pharmaceutical science.
Professional Profiles:
š Education:
Jadavpur University( WORKED @CSIR-IICB): Kolkata, West Bengal, IN,2011-06-13 to 2014-06-27 | PhD (PHARMACY DEPARTMENT),Education, Show more detail, Source,:, ASHOK BEHERA ,National Institute of Pharmaceutical Education and Research Kolkata: Jadavpur, West Bengal, IN,2007-11-10 to 2009-06-30 | MS Pharm(Medicinal Chemistry) (PHARMACY),Education ,Show more detail, Source,: ,ASHOK BEHERA
RESEARCH GRANT/FUNDING :
ā¢ DST-SERB-TARE, File. No. TAR/2020/000151 āSynthesis, characterization and biological evaluation of smart novel n another anostic for cancerā. As PI Dec 2020. For 3 yr/Grant amount: 16.3 Lakhs.,ā¢ Synthesis, characterization and in-vitro evaluation of new 5FU-Octreotide conjugates for targeted chemotherapy. Project no. DITU/R&D/2021/2/ Pharmaceutical science. For 2 yr/Grant amount: 2 Lakhs.
TECHNICAL SUPPORTIVE SKILLS :
- Peptidomimetics and Peptide Conjugates as Therapeutics and Drug Delivery:
- Design and development of peptidomimetics and peptide conjugates for therapeutic applications.
- Exploration of their potential in drug delivery systems.
- Receptor-Specific Targeted Drug Delivery:
- Investigating methods for delivering drugs specifically to target receptors.
- Computer-Aided Drug Design:
- Utilizing computational tools and techniques for drug design.
- Analytical Method Development:
- Developing analytical methods for characterizing and quantifying compounds.
- Expertise in HPLC method development.
- Organic Synthesis and Purification:
- Proficiency in solid-phase peptide synthesis and stapled peptide synthesis.
- Experience in various organic synthetic reactions, especially bioconjugation techniques and microwave synthesis.
- Purification techniques include column chromatography, HPLC, distillation, and crystallization.
- Analytical Techniques and Structure Elucidation:
- Using FT-IR, NMR (H1, C13, 2D), Mass spectrometry (LC-MS, MS-MS), CHN analyzer, polarimeter, and X-ray crystallography for structure elucidation.
- Biological Studies:
- Conducting cell line assays, mechanistic studies, and animal studies related to anticancer drug discovery.
- Biological evaluation through radiolabeling of 99mTc, in vitro assays, receptor binding assays, internalization studies, and in vivo studies.
- Nuclear Imaging Techniques:
- Synthesizing radiolabeled anticancer drug molecules for tumor imaging using SPECT and other nuclear medical imaging techniques.
- Software Applications:
- Proficiency in various software applications relevant to research, including Autodock Vina, Chimera, PyRx virtual docking, ChemBioOffice, Mendeley, GraphPad, Reaxys, SciFinder, MS-Office, etc.
Publication Top Note :
- Copper-Catalyzed Electrophilic Ortho C(sp2)āH Amination of Aryl Amines: Dramatic Reactivity of Bicyclic System
- Cited by: 33
- Year: 2019
- Synthesis, radiolabeling, and preclinical evaluation of a new octreotide analog for somatostatin receptorāpositive tumor scintigraphy
- Cited by: 23
- Year: 2012
- Synthesis, characterization, conformational analysis of a cyclic conjugated octreotate peptide and biological evaluation ofĀ 99mTc-HYNIC-His3-Octreotate as novelĀ ā¦
- Cited by: 13
- Year: 2013
- Synthesis, radiolabelling and biodistribution of HYNIC-Tyr {sup 3} octreotide. A somatostatin receptor positive tumour imaging agent
- Cited by: 12
- Year: 2011
- Synthesis, radiolabelling and biodistribution of HYNIC-Tyr3Ā octreotide: a somatostatin receptor positive tumour imaging agent
- Cited by: 12
- Year: 2011
- Synthesis, characterization, biodistribution and scintigraphy ofĀ 99mTc-paclitaxel: a potential tracer of paclitaxel
- Cited by: 8
- Year: 2015
- A Modified Synthetic Approach to Optically Pure Benzoxazepines from Amino Acid Precursors Using Intramolecular Buchwald-Hartwig CO Bond-Formation Reaction
- Cited by: 7
- Year: 2011
- Radiolabeled novel peptide for imaging somatostatin-receptor expressing tumor: synthesis and radiobiological evaluation
- Cited by: 3
- Year: 2014
- Smart Advancements for Targeting Solid Tumors via Protein and Peptide Drug Delivery (PPD)
- Cited by: 1
- Year: 2022
- Systematic Review on Nobiletin a Phyto-Constitu-ent Having Potential to Prevent and Manage Multiple Ailments
- Cited by: 1
- Year: 2021